Two Europa League titles and a Copa del Rey have meant the trophy cabinet has been well stocked and while players have come and gone, Atleti's current squad is as strong as they have ever had.
Los Rojiblancos should be confident of getting off to a winning start at home to Zenit St Petersburg and William Hill price them at just 11/20 1.55 for the win. The Russians, meanwhile, are offered at 5/1 6.00,with the draw available at 3/1 4.00.
As we saw on Tuesday with Real Sociedad, decent domestic form does not always translate into a European performance yet Diego Simeone's side have been imperious so far this season and there is little reason to back against them.
While backing them outright does not appeal at the price quoted, investing in them to win the first half at 21/20 2.05 could be worthy of some consideration. Atleti have one of the best recent home records in any of the major European leagues.
They are not always attractive to watch but they are usually extremely effective.
